Nimbolide and isonimbolide

被引：11

作者：

Anitha, G.

Raj, J. Josepha Lourdu

Narasimhan, S.

Solomon, K. Anand

Rajan, S. S.

机构：

[1] Asthagiri Herbal Res Fdn, Madras 600059, Tamil Nadu, India

[2] Univ Madras, Dept Crystallog & Biophys, Madras 600032, Tamil Nadu, India

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2006年 / 8卷 / 05期

关键词：

ninibolide; isonimbolide; BF3 center dot OEt2-(C4H9)(4)NBr;

D O I：

10.1080/10286020500173267

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Nimbolide 1, a potent molecule of biological significance, was isolated. Attempts were made to cleave the ether linkage in nimbolide using boron trifluoride etherate in the presence of tetrabutyl ammonium bromide so as to generate a ring-opened structure akin to azadirachfins, which are known to possess excellent antifeedant properties. However, a novel rearranged product was envisaged during the course of the reaction, which was determined as isonimbolide 2 a structural isomer of nimbolide through spectroscopic methods.

引用

页码：445 / 449

页数：5

共 13 条

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BABU PBS, Patent No. 1278SDEL92

[2] SYNTHETIC AND MECHANISTIC STUDIES OF THE RETRO-CLAISEN REARRANGEMENT - AN EXAMPLE OF CATION ACCELERATION OF A (3,3)-SIGMATROPIC REARRANGEMENT [J].