Lactobacillus plantarum- : survival, functional and potential probiotic properties in the human intestinal tract

被引：430

作者：

de Vries, Maalke C.

Vaughan, Elaine E.

Kleerebezem, Michiel

de Vos, Willem M.

机构：

[1] Wageningen Univ, Microbiol Lab, NL-6703 CT Wageningen, Netherlands

[2] Wageningen Ctr Food Sci, NL-6700 AN Wageningen, Netherlands

[3] NIZO Food Res, NL-6710 BA Ede, Netherlands

来源：

INTERNATIONAL DAIRY JOURNAL | 2006年 / 16卷 / 09期

关键词：

Lactobacillus plantarum; human intestinal tract; molecular analysis; physiological effects; living vaccine;

D O I：

10.1016/j.idairyj.2005.09.003

中图分类号：

TS2 [食品工业];

学科分类号：

0832 [食品科学与工程];

摘要：

Lactobacillus plantarum is a versatile lactic acid bacterium that is encountered in a range of environmental niches, has a proven ability to survive gastric transit, and can colonize the intestinal tract of human and other mammals. Several studies describe the effects of L. plantarum consumption on human physiology. The availability of the complete genome sequence of L. plantarum WCFS1 makes it a suitable model to explore the molecular mechanisms underlying the targeted intestinal properties of this species. An increasing number of studies address the development of L. plantarum into an ingestible living vaccine. Furthermore, studies are emerging to determine the activity of L. plantarum in the human intestinal tract. This review discusses the studies of the safety and survival of L. plantarum in the human intestinal tract, the effects of this bacterium on the host and it provides an overview of the molecular studies addressing the activity of L. plantarum in the human gut environment. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：1018 / 1028

页数：11

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