Intramolecular inverse electron demand Diels-Alder reactions of tryptamine with tethered heteroaromatic azadienes

被引:76
作者
Benson, SC [1 ]
Lee, L [1 ]
Yang, L [1 ]
Snyder, JK [1 ]
机构
[1] Boston Univ, Dept Chem, Boston, MA 02215 USA
基金
美国国家科学基金会;
关键词
cycloaddition; indoles; tetrazines; triazines;
D O I
10.1016/S0040-4020(00)00003-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
1,2,4,5-Tetrazines and 1,2,4-triazines tethered to tryptamine via the ethylamine side chain undergo intramolecular inverse electron demand cycloadditions to produce adducts with the [ABazaCE]-ring skeleton of the Aspidosperma alkaloids. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1165 / 1180
页数:16
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