AAV hits the genomic bull's-eye

被引:5
作者
Engelhardt, John F. [1 ]
机构
[1] Univ Iowa, Coll Med, Dept Cell Biol & Anat, Iowa City, IA 52242 USA
关键词
D O I
10.1038/nbt0806-949
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Adeno-associated virus mediates correction of genetic mutations in mouse liver.
引用
收藏
页码:949 / 950
页数:2
相关论文
共 10 条
[1]   Sequence-specific modification of genomic DNA by small DNA fragments [J].
Gruenert, DC ;
Bruscia, E ;
Novelli, G ;
Colosimo, A ;
Dallapiccola, B ;
Sangiuolo, F ;
Goncz, KK .
JOURNAL OF CLINICAL INVESTIGATION, 2003, 112 (05) :637-641
[2]   Gene targeting with viral vectors [J].
Hendrie, PC ;
Russell, DW .
MOLECULAR THERAPY, 2005, 12 (01) :9-17
[3]   Targeted single-base correction by RNA-DNA oligonucleotides [J].
Igoucheva, O ;
Yoon, K .
HUMAN GENE THERAPY, 2000, 11 (16) :2307-2312
[4]   Gene targeting in vivo by adeno-associated virus vectors [J].
Miller, Daniel G. ;
Wang, Pei-Rong ;
Petek, Lisa M. ;
Hirata, Roli K. ;
Sands, Mark S. ;
Russell, David W. .
NATURE BIOTECHNOLOGY, 2006, 24 (08) :1022-1026
[5]   Human gene targeting by adeno-associated virus vectors is enhanced by DNA double-strand breaks [J].
Miller, DG ;
Petek, LM ;
Russell, DW .
MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (10) :3550-3557
[6]   Gene targeting using zinc finger nucleases [J].
Porteus, MH ;
Carroll, D .
NATURE BIOTECHNOLOGY, 2005, 23 (08) :967-973
[7]   Efficient gene targeting mediated by adeno-associated virus and DNA double-strand breaks [J].
Porteus, MH ;
Cathomen, T ;
Weitzman, MD ;
Baltimore, D .
MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (10) :3558-3565
[8]   The potential for gene repair via triple helix formation [J].
Seidman, MM ;
Glazer, PM .
JOURNAL OF CLINICAL INVESTIGATION, 2003, 112 (04) :487-494
[9]   Site-specific strand bias in gene correction using single-stranded oligonucleotides [J].
Sorensen, CB ;
Krogsdam, AM ;
Andersen, MS ;
Kristiansen, K ;
Bolund, L ;
Jensen, TG .
JOURNAL OF MOLECULAR MEDICINE-JMM, 2005, 83 (01) :39-49
[10]   Persistent failures in gene repair [J].
van der Steege, G ;
Schuilenga-Hut, PHL ;
Buys, CHCM ;
Scheffer, H ;
Pas, HH ;
Jonkman, MF .
NATURE BIOTECHNOLOGY, 2001, 19 (04) :305-306