2,3-Functionalization of furans, benzofurans and thiophenes via magnesiation and sulfoxide-magnesium exchange

被引：58

作者：

Melzig, Laurin ^{[1
]}

Rauhut, Christian B. ^{[1
]}

Knochel, Paul ^{[1
]}

机构：

[1] Univ Munich, Munich, Germany

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 24期

关键词：

ALKENYL HALIDES; ROUTE; DERIVATIVES; REAGENTS; ARENES; ARYL;

D O I：

10.1039/b907330b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The use of TMPMgCl center dot LiCl and iPrMgCl center dot LiCl allows a sequential 2,3-difunctionalization of various 2-arylsulfinyl furans, thiophenes and benzofurans. Subsequent use of the same reagents permits a selective full functionalization of all 4 positions of the furan and thiophene scaffolds.

引用

收藏

页码：3536 / 3538

页数：3

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