Microwave-assisted rapid and straightforward synthesis of 2-aryl-4-quinolones from acylated 2′-aminoacetophenones

被引：64

作者：

Ding, Derong ^{[1
]}

Li, Xin ^{[1
]}

Wang, Xin ^{[1
]}

Du, Yongli ^{[1
]}

Shen, Jingkang ^{[1
]}

机构：

[1] Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, Shanghai Inst Biol Sci, Shanghai 201203, Peoples R China

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 39期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/j.tetlet.2006.07.117

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The syntheses of a diverse set of 2-aryl-4-quinolone derivatives were achieved by exposing corresponding acylated 2'aminoacetophenones to microwave irradiation in the presence of NaOH. The microwave accelerated cyclizations were complete within 10-22 min at 120 degrees C giving 57-95% isolated yields. (c) 2006 Elsevier Ltd. All rights reserved.

引用

收藏

页码：6997 / 6999

页数：3

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