Importance link function estimation for Markov chain Monte Carlo methods

This article focuses on improving estimation for Markov chain Monte Carlo simulation. The proposed methodology is based upon the use of importance link functions. With the help of appropriate importance sampling weights, effective estimates of functionals are developed. The method is most easily applied to irreducible Markov chains, where application is typically immediate. An important conceptual point is the applicability of the method to reducible Markov chains through the use of many-to-many importance link functions. Applications discussed include estimation of marginal genotypic probabilities for pedigree data, estimation for models with and without influential observations, and importance sampling for a target distribution with thick tails.