Hypomania as an adverse effect of subthalamic nucleus stimulation: report of two cases

被引：85

作者：

Mandat, T. S.

Hurwitz, T.

Honey, C. R.

机构：

[1] Univ British Columbia, Div Neurosurg, Vancouver, BC V5Z 4E5, Canada

[2] Univ British Columbia, Dept Psychiat, Vancouver, BC, Canada

来源：

ACTA NEUROCHIRURGICA | 2006年 / 148卷 / 08期

关键词：

deep brain stimulation; subthalamic nucleus; hypomania;

D O I：

10.1007/s00701-006-0795-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Mania following subthalamic nucleus (STN) deep brain stimulation (DBS) is well described and obvious to both the patient and their physician. The authors describe two patients who developed hypomania following STN-DBS but were unaware of their mood disturbance. Two Parkinson's patients with no previous mood disorders received bilateral STN electrodes. Both experienced dramatic improvement in their motor function and neither complained of any side effects. Their families reported detrimental hypomanic behaviour. Readjusting the stimulation parameters resolved the hypomania with continued motor benefits. The authors draw attention to potential adverse effects of STN-DBS that might be neglected by patients.

引用

页码：895 / 898

页数：4

共 23 条

[1] Transient acute depression induced by high-frequency deep-brain stimulation
Bejjani, BP
Damier, P
Arnulf, I
Thivard, L
Bonnet, AM
Dormont, D
Cornu, P
Pidoux, B
Samson, Y
Agid, Y
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (19) : 1476 - 1480
[2] Aggressive behavior induced by intraoperative stimulation in the triangle of Sano
Bejjani, BP
Houeto, JL
Hariz, M
Yelnik, J
Mesnage, V
Bonnet, AM
Pidoux, B
Dormont, D
Cornu, P
Agid, Y
[J]. NEUROLOGY, 2002, 59 (09) : 1425 - 1427
[3] Effect on mood of subthalamic DBS for Parkinson's disease - A consecutive series of 24 patients
Berney, A
Vingerhoets, F
Perrin, A
Phil, L
Guex, P
Villemure, JG
Burkhard, PR
Benkelfat, C
Ghika, J
[J]. NEUROLOGY, 2002, 59 (09) : 1427 - 1429
[4] The substantia nigra as a site of synaptic integration of functionally diverse information arising from the ventral pallidum and the globus pallidus in the rat
Bevan, MD
Smith, AD
Bolam, JP
[J]. NEUROSCIENCE, 1996, 75 (01) : 5 - 12
[5] Lesion location and poststroke depression - Systematic review of the methodological limitations in the literature
Bhogal, SK
Teasell, R
Foley, N
Speechley, M
[J]. STROKE, 2004, 35 (03) : 794 - 802
[6] CUMMINGS JL, 1984, AM J PSYCHIAT, V141, P1048
[7] Depression leading to attempted suicide after bilateral subthalamic nucleus stimulation for Parkinson's disease
Doshi, PK
Chhaya, N
Bhatt, MH
[J]. MOVEMENT DISORDERS, 2002, 17 (05) : 1084 - 1085
[8] Acute psychotropic effects of bilateral subthalamic nucleus stimulation and levodopa in Parkinson's disease
Funkiewiez, A
Ardouin, C
Krack, P
Fraix, V
Van Blercom, N
Xie, J
Moro, E
Benabid, AL
Pollak, P
[J]. MOVEMENT DISORDERS, 2003, 18 (05) : 524 - 530
[9] POSTSTROKE DEPRESSION - IS THERE A PATHOANATOMIC CORRELATE FOR DEPRESSION IN THE POSTACUTE STAGE OF STROKE
HERRMANN, M
BARTELS, C
SCHUMACHER, M
WALLESCH, CW
[J]. STROKE, 1995, 26 (05) : 850 - 856
[10] Subthalamic nucleus stimulation restores glucose metabolism in associative and limbic cortices and in cerebellum: Evidence from a FDG-PET study in advanced Parkinson's disease
Hilker, R
Voges, T
Weisenbach, S
Kalbe, E
Burghaus, L
Ghaemi, M
Lehrke, R
Koulousakis, A
Herholz, K
Sturm, V
Heiss, WD
[J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2004, 24 (01) : 7 - 16

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