Paroxetine associated hepatotoxicity: A report of 3 cases and a review of the literature

被引：33

作者：

Azaz-Livshits, T ^{[1
]}

Hershko, A ^{[1
]}

Ben-Chetrit, E ^{[1
]}

机构：

[1] Hadassah Univ Hosp, Dept Med & Clin Pharmacol, IL-91120 Jerusalem, Israel

来源：

PHARMACOPSYCHIATRY | 2002年 / 35卷 / 03期

关键词：

D O I：

10.1055/s-2002-31515

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

We recently encountered 3 patients who had developed reversible paroxetine-associated hepatotoxicity. Two of the patients were over 80 years old and their hepatitis was accompanied by hyponatremia. In the third case, hepatitis was associated with multiple Organ failure and the co-administration of trazodone. Here, we will discuss the possible role Of preexisting Fisk factors in the development of paroxetine hepatotoxicity and review the relevant literature.

引用

页码：112 / 115

页数：4

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