A convenient synthesis of chiral nonracemic vinyl aziridines

被引：86

作者：

Morton, D

Pearson, D

Field, RA

Stockman, RA ^{[1
]}

机构：

[1] Univ E Anglia, Sch Chem Sci & Pharm, Norwich NR4 7TJ, Norfolk, England

[2] Millenium Pharmaceut UK, Cambridge CB1 6ET, England

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 14期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1021/ol049252l

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation of a range of alkyl and aryl chiral vinyl aziridines was achieved in high yield and stereoselectivity, and with excellent diastereoselectivity, by reaction of tert-butylsulfinylimines with the ylide derived from S-allyl tetrahydrothiophenium bromide.

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页码：2377 / 2380

页数：4

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