Sensory neuropathy and anti-Hu antibodies in a patient with seminoma

被引：11

作者：

Gabriel, CM

Gregson, NA

Hughes, RAC

机构：

[1] Department of Neurology, UMDS, Guy's Hospital

来源：

EUROPEAN JOURNAL OF NEUROLOGY | 1996年 / 3卷 / 05期

关键词：

paraneoplastic syndromes; peripheral neuropathy; testicular neoplasm; anti-neuronal antibody;

D O I：

10.1111/j.1468-1331.1996.tb00252.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A man with subacute sensory neuronopathy (SSN) had a stage 1 seminoma. His serum and cerebrospinal fluid (CSF) contained anti-Hu antibodies (type 1 anti-neuronal nuclear antibodies, ANNA-I). Following orchidectomy, radiotherapy, prednisolone, plasma exchange and intravenous immunoglobulin the antineuronal antibody titre fell and the neuropathy improved.

引用

收藏

页码：471 / 474

页数：4

相关论文

共 16 条

[1] AUTOANTIBODIES IN PARA-NEOPLASTIC SYNDROMES ASSOCIATED WITH SMALL-CELL LUNG-CANCER [J].

ANDERSON, NE ;

ROSENBLUM, MK ;

GRAUS, F ;

WILEY, RG ;

POSNER, JB .

NEUROLOGY, 1988, 38 (09) :1391-1398

[2]

BALLIEJOHNSON H, 1985, BRIT J CANCER, V52, P495

[3] SERONEGATIVITY FOR TYPE-1 ANTINEURONAL NUCLEAR ANTIBODIES (ANTI-HU) IN SUBACUTE SENSORY NEURONOPATHY PATIENTS WITHOUT CANCER [J].

CHALK, CH ;

LENNON, VA ;

STEVENS, JC ;

WINDEBANK, AJ .

NEUROLOGY, 1993, 43 (11) :2209-2211

[4] ANTI-HU-ASSOCIATED PARANEOPLASTIC ENCEPHALOMYELITIS SENSORY NEURONOPATHY - A CLINICAL-STUDY OF 71 PATIENTS [J].

DALMAU, J ;

GRAUS, F ;

ROSENBLUM, MK ;

POSNER, JB .

MEDICINE, 1992, 71 (02) :59-72

[5] NEUROLOGIC PARANEOPLASTIC ANTIBODIES (ANTI-YO, ANTI-HU, ANTI-RI) - THE EASE FOR A NOMENCLATURE BASED ON ANTIBODY AND ANTIGEN-SPECIFICITY [J].

DALMAU, J ;

POSNER, JB .

NEUROLOGY, 1994, 44 (12) :2241-2246

[6] UNUSUAL PRESENTATION OF SEMINOMA OF TESTIS [J].

EVANS, CC ;

KAUFMAN, HD .

BRITISH JOURNAL OF SURGERY, 1971, 58 (09) :703-&

[7] IMMUNOHISTOCHEMICAL ANALYSIS OF THE IMMUNE-REACTION IN THE NERVOUS-SYSTEM IN PARANEOPLASTIC ENCEPHALOMYELITIS [J].

GRAUS, F ;

RIBALTA, T ;

CAMPO, E ;

MONFORTE, R ;

URBANO, A ;

ROZMAN, C .

NEUROLOGY, 1990, 40 (02) :219-222

[8] NEURONAL ANTINUCLEAR ANTIBODY IN SENSORY NEURONOPATHY FROM LUNG-CANCER [J].

GRAUS, F ;

CORDONCARDO, C ;

POSNER, JB .

NEUROLOGY, 1985, 35 (04) :538-543

[9] SENSORY NEURONOPATHY AND SMALL-CELL LUNG-CANCER - ANTINEURONAL ANTIBODY THAT ALSO REACTS WITH THE TUMOR [J].

GRAUS, F ;

ELKON, KB ;

CORDONCARDO, C ;

POSNER, JB .

AMERICAN JOURNAL OF MEDICINE, 1986, 80 (01) :45-52

[10] ANTIBODIES TO CEREBELLAR PURKINJE-CELLS IN PATIENTS WITH PARA-NEOPLASTIC CEREBELLAR DEGENERATION AND OVARIAN-CARCINOMA [J].

GREENLEE, JE ;

BRASHEAR, HR .

ANNALS OF NEUROLOGY, 1983, 14 (06) :609-613