Capillary affinity gel electrophoresis: new technique for specific recognition of DNA sequence and the mutation detection on DNA

被引:10
作者
Baba, Y [1 ]
机构
[1] Univ Tokushima, Fac Pharmaceut Sci, Dept Med Chem, Tokushima 7708505, Japan
来源
JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS | 1999年 / 41卷 / 2-3期
关键词
reviews; capillary electrophoresis; affinity; DNA; mutation detection;
D O I
10.1016/S0165-022X(99)00040-8
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The present state of studies on capillary affinity gel electrophoresis, which is a new technique for the specific recognition of a target DNA sequence, is reviewed. This article includes the principle, theory, methods, and applications of this technology. The great potential of capillary affinity gel electrophoresis for the sequence-specific recognition of DNA and the detection of mutations in specific genes is illustrated. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:91 / 101
页数:11
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