Diagnostic value of C-reactive protein in discriminating fungal from nonfungal pulmonary infiltrates in patients with hematologic malignancies

被引：6

作者：

Offidani, Massimo ^{[1
]}

Corvatta, Laura

Malerba, Lara

Piersantelli, Maria-Novella

Manso, Esther

Leoni, Pietro

机构：

[1] Univ Politecn Marche, Osped Riuniti, Clin Ematol, Ancona, Italy

[2] Osped San Salvatore, Div Ematol, Pesaro, Italy

[3] Univ Politecn Marche, Osped Riuniti, Dipartimento Microbiol, Ancona, Italy

来源：

SUPPORTIVE CARE IN CANCER | 2006年 / 14卷 / 08期

关键词：

C-reactive protein; hematologic malignancies; fungal infection; neutropenia;

D O I：

10.1007/s00520-006-0030-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The objective of this study was to assess the utility of C-reactive protein (CRP) on differential diagnosis of pulmonary infiltrates occurring in 143 febrile patients with hematologic malignancies. Serum CRP level, measured on the first day of pneumonia, was significantly higher in patients with fungal lung infiltrates than in those with nonfungal pneumonia (22.3 mg/dl vs 7.3 mg/dl; p < 0.0001). Predictive factors for fungal pneumonia were CRP level higher than 10 mg/dl, neutropenia longer than 10 days, and active underlying disease.

引用

页码：874 / 877

页数：4