jViz.Rna -: An interactive graphical tool for visualizing RNA secondary structure including pseudoknots

被引:14
作者
Wiese, Kay C. [1 ]
Glen, Edward [1 ]
机构
[1] Simon Fraser Univ, Sch Comp Sci, 13450 102nd Ave, Surrey, BC V3T 5X3, Canada
来源
19TH IEEE INTERNATIONAL SYMPOSIUM ON COMPUTER-BASED MEDICAL SYSTEMS, PROCEEDINGS | 2006年
关键词
D O I
10.1109/CBMS.2006.104
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
In order for structure prediction researchers to better understand the results of their algorithms and to enable life science researchers to interpret RNA structure easily, it is helpful to provide them with a flexible and powerful tool for RNA secondary structure visualization. jViz.Rna is a multi-platform visualization tool capable of displaying RNA secondary structures encoded in a variety of file formats. A single structure can be shown using the linear Feynman, circular Feynman, dot plot, and classical structure visualization models. ne resulting drawings are dynamic and can easily be further modified by the user Any of the drawings produced can be saved to disk enabling easy dissemination. The unique usage of a spring model for classical structure drawing allows for clear visualization of pseudoknots with minimal overlaps. The addition of a locality tool allows for the isolation of pseudoknotted regions or other regions of interest.
引用
收藏
页码:659 / +
页数:3
相关论文
共 14 条
[11]   Comparison of P-RnaPredict and mfold -: algorithms for RNA secondary structure prediction [J].
Wiese, KC ;
Hendriks, A .
BIOINFORMATICS, 2006, 22 (08) :934-942
[12]   jViz.Rna -: A Java']Java tool for RNA secondary structure visualization [J].
Wiese, KC ;
Glen, E ;
Vasudevan, A .
IEEE TRANSACTIONS ON NANOBIOSCIENCE, 2005, 4 (03) :212-218
[13]   A permutation-based genetic algorithm for the RNA folding problem: a critical look at selection strategies, crossover operators, and representation issues [J].
Wiese, KC ;
Glen, E .
BIOSYSTEMS, 2003, 72 (1-2) :29-41
[14]   Mfold web server for nucleic acid folding and hybridization prediction [J].
Zuker, M .
NUCLEIC ACIDS RESEARCH, 2003, 31 (13) :3406-3415