Hepatitis C:: molecular virology and antiviral targets

被引：51

作者：

Moradpour, D ^{[1
]}

Brass, V ^{[1
]}

Gosert, R ^{[1
]}

Wölk, B ^{[1
]}

Blum, HE ^{[1
]}

机构：

[1] Univ Freiburg, Dept Med 2, D-79106 Freiburg, Germany

来源：

TRENDS IN MOLECULAR MEDICINE | 2002年 / 8卷 / 10期

关键词：

D O I：

10.1016/S1471-4914(02)02395-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chronic hepatitis C is a leading cause of liver cirrhosis and hepatocellular carcinoma worldwide. Although current treatment options are limited, progress in understanding the molecular virology of hepatitis C has led to the identification of novel antiviral targets. Moreover, in vitro and in vivo model systems have been developed that allow systematic evaluation of new therapeutic strategies. This review details current concepts in molecular virology and emerging therapies for hepatitis C.

引用

页码：476 / 482

页数：7

共 73 条

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