The hitchhiking effect of an autosomal meiotic drive gene

被引：15

作者：

Chevin, Luis-Miguel ^{[1
]}

Hospital, Frederic ^{[1
]}

机构：

[1] Univ Paris 11, INRA, UMR Genet Vegetale Moulon, CNRS,INA PG, F-91190 Gif Sur Yvette, France

来源：

GENETICS | 2006年 / 173卷 / 03期

关键词：

D O I：

10.1534/genetics.105.052977

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Transmission-ratio distortion is a departure from a 1:1 segregation of alleles in the gametes of a heterozygous individual. The so-called driving allele is strongly selected regardless of its effect on the fitness of the carrying individual. It may then have an important impact on neutral polymorphism due to the genetic hitchhiking effect. We study this hitchhiking effect in the case of true meiotic drive in autosomes and show that it is more dependent on the recombination rate than in the classical case of a gene positively selected at the organism level.

引用

页码：1829 / 1832

页数：4

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