Transcriptomics and proteomics: Tools for the identification of novel drug targets and vaccine candidates for tuberculosis

被引：34

作者：

Betts, JC ^{[1
]}

机构：

[1] GlaxoSmithKline Res & Dev Ltd, Resp Pathogens, Stevenage SG1 2NY, Herts, England

来源：

IUBMB LIFE | 2002年 / 53卷 / 4-5期

关键词：

DNA microarray; drug target; Mycobacterium tuberculosis; proteome; transcriptome; vaccine candidate;

D O I：

10.1080/15216540212651

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The availability of the complete genome sequence of Mycobacterium tuberculosis has revolutionised many areas of tuberculosis research and facilitated functional genomics studies. Most notably, transcriptomics and proteomics have become important tools in gaining increased understanding of the biology of M. tuberculosis and offer the promise of being able to deliver novel drug targets and vaccine candidates.

引用

页码：239 / 242

页数：4

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