Synthesis of the pyrrolo[2,3-c]carbazole core of the dictyodendrins

被引：41

作者：

Ayats, Carles ^{[1
]}

Soley, Roger ^{[1
]}

Albericio, Fernando ^{[1
,2
]}

Alvarez, Mercedes ^{[1
,3
]}

机构：

[1] Univ Barcelona, Inst Res Biomed, E-08028 Barcelona, Spain

[2] Univ Barcelona, Dept Organ Chem, E-08028 Barcelona, Spain

[3] Univ Barcelona, Organ Chem Lab, Fac Pharm, E-08028 Barcelona, Spain

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2009年 / 7卷 / 05期

关键词：

RECEPTOR-ANTAGONIST; DISCOVERY; INHIBITORS; INDOLES; SPONGE;

D O I：

10.1039/b822933n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The pyrrolo[2,3-c] carbazole 1, the common core of the marine alkaloids known as the dictyodendrins, has been synthesised. The sequence is based on a Suzuki cross-coupling reaction between the pyrrole fragment 2 and the indole fragment 3, followed by tandem photochemical 6 pi-electrocyclisation/aromatisation.

引用

页码：860 / 862

页数：3

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