Re(CO)5Br-catalyzed addition of carboxylic acids to terminal alkynes:: A high anti-Markovnikov and recoverable homogeneous catalyst

被引：67

作者：

Hua, RM ^{[1
]}

Tian, X ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Beijing 100084, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 17期

关键词：

D O I：

10.1021/jo049455n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The addition of carboxylic acids to terminal alkynes is efficiently catalyzed by the early transition-metal complex Re(CO)(5)Br in toluene or n-heptane at 110 degreesC in an air atmosphere, affording the anti-Markovnikov adducts in good yields with high selectivity. In most cases, the reactions afford unusual Z-adduct predominantly. When n-heptane was used as solvent, Re(CO)(5)Br can be partly recovered from the reaction mixture.

引用

页码：5782 / 5784

页数：3

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