Timeline - MALT lymphoma: from morphology to molecules

被引:336
作者
Isaacson, PG
Du, MQ
机构
[1] UCL, Royal Free & Univ Coll Med Sch, Dept Histopathol, London WC1E 6JJ, England
[2] Univ Cambridge, Addenbrookes Hosp, Dept Pathol, Cambridge CB2 2QQ, England
关键词
D O I
10.1038/nrc1409
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Hints that the growth of some lymphomas is stimulated by bacterial antigens and can be controlled by treatment with antibiotics first emerged in the 1970s. Subsequently, a specific type of B-cell lymphoma mucosa-associated lymphoid tissue ( MALT) lymphoma - was identified that is associated with bacterial infection and auto-antigen stimulation. This article chronicles the clinical, immunological and molecular developments in our knowledge of MALT lymphoma and the factors that contribute to its pathogenesis.
引用
收藏
页码:644 / 653
页数:10
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