Detection and Characterization of Focal Hepatic Tumors: A Comparison of T2-Weighted MR Images Before and After the Administration of Gadoxectic Acid

被引:40
作者
Kim, Young Kon [1 ]
Kwak, Hyo Sung [1 ]
Kim, Chong Soo [1 ]
Han, Young Min [1 ]
机构
[1] Chonbuk Natl Univ, Med Sch & Hosp, Dept Diagnost Radiol, Jeonju 561180, Jeonbuk, South Korea
关键词
liver; neoplasm; magnetic resonance imaging; contrast agents; gadoxetic acid; GD-EOB-DTPA; LIVER-LESIONS; SPIN-ECHO; ENHANCEMENT; CT; CONSPICUOUSNESS; EXPERIENCE;
D O I
10.1002/jmri.21839
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
100231 [临床病理学]; 100902 [航空航天医学];
摘要
Purpose: To evaluate if T2-weighted images (T2WI) after administration of gadoxetic acid have diagnostic capability comparable to precontrast T2WI in the detection and characterization of focal liver lesions. Materials and Methods: Eighty patients with 128 liver lesions (71 hepatocellular carcinomas, 35 metastases, and 22 hemangiomas) underwent gadoxetic acid-enhanced T1WI and precontrast and postcontrast turbo spin echo-short tau inversion recovery (TSE-STIR) and respiratory triggered (RT)-TSE. The sensitivity for malignancy with combining T2WIs and enhanced T1WIs was evaluated and percentage of signal intensity loss (PSIL) and lesion-liver contrast to noise ratio (CNR) were calculated for T2WIs. Lesion characterization with T2WIs as solid and nonsolid was evaluated using kappa statistics. Results: The PSIL was higher with TSE-STIR than with RT-TSE (P = 0.0001). The malignancy-liver CNRs on postcontrast T2WIs were higher than on precontrast T2WIs (P = 0.0001). Sensitivity for malignancy by combining postcontrast T2WIs and T1WIs (93.0% [hepatocellular carcinoma, HCC]; 97.1% [metastases]) was comparable to sensitivity of combining precontrast T2WIs and postcontrast T1WIs (91.6% [HCC]: 88.6% [metastases]). Kappa values for T2WIs indicated excellent agreement (k = 0.935). Conclusion: Gadoxetic acid-enhanced T2WIs showed a comparable diagnostic capability to precontrast T2WIs for the detection and characterization of hepatic tumors.
引用
收藏
页码:437 / 443
页数:7
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