A plant orthologue of RNase L inhibitor (RLI) is induced in plants showing RNA interference

被引:36
作者
Braz, ASK
Finnegan, J
Waterhouse, P
Margis, R [1 ]
机构
[1] Univ Fed Rio Janeiro, LGMV, Dept Genet, Inst Biol,CCS, BR-21944970 Rio De Janeiro, Brazil
[2] Univ Fed Rio de Janeiro, Dept Bioquim, Inst Quim, Rio de Janeiro, Brazil
[3] CSIRO, Plant Ind, Canberra, ACT, Australia
关键词
RNase L inhibitor; RNAi; PTGS; RNA silencing;
D O I
10.1007/s00239-004-2600-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
RNase L inhibitors (RLIs) correspond to a group of soluble proteins from the large ATP binding cassette (ABC) family of proteins. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains. Orthologous RLI sequences with more than 48% identity have been found from Archea to Eukaryota, but have not as yet been identified in Eubacteria. Some organisms, like Arabidopsis thaliana and human, have paralogous genes with differential expression patterns, the function of which remains to be determined. Expression of Arabidopsis RLI2 was slightly increased in transgenic plants showing RNA interference, suggesting a role in this pathway.
引用
收藏
页码:20 / 30
页数:11
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