New alkaloids from a South African latrunculid sponge

被引：64

作者：

Hooper, GJ

DaviesColeman, MT

KellyBorges, M

Coetzee, PS

机构：

[1] RHODES UNIV,DEPT CHEM,ZA-6140 GRAHAMSTOWN,SOUTH AFRICA

[2] NAT HIST MUSEUM,DEPT ZOOL,LONDON SW7 5BD,ENGLAND

[3] UNIV PORT ELIZABETH,DEPT ZOOL,ZA-6000 PORT ELIZABETH,SOUTH AFRICA

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 39期

关键词：

D O I：

10.1016/0040-4039(96)01560-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The structures of two new bispyrroloiminoquinone alkaloids, tsitsikammamine A (1) and tsitsikammamine B (2) and two new pyrroloiminoquinone alkaloids 14-bromodiscorhabdin C (3) and 14-bromodihydrodiscorhabdin C (4) were determined spectroscopically. Compounds 1 and 2 are the first bispyrroloiminoquinone alkaloids to be isolated from a marine sponge while compounds 3 and 4 are the first reported discorhabdin metabolites with a C-14 substituent. All four compounds exhibit antimicrobial activity. Copyright (C) 1996 Elsevier Science Ltd

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页码：7135 / 7138

页数：4

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