Paradoxical recurrent meningitis following therapy of cryptococcal meningitis: an immune reconstitution syndrome after initiation of highly active antiretroviral therapy

被引:51
作者
King, MD [1 ]
Perlino, CA [1 ]
Cinnamon, J [1 ]
Jernigan, JA [1 ]
机构
[1] Emory Univ, Sch Med, Div Infect Dis, Atlanta, GA 30303 USA
关键词
cryptococcal meningitis; immune reconstitution; AIDS; highly active antiretroviral therapy;
D O I
10.1258/095646202760326516
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We report a case of paradoxical recurrent meningitis in response to initiation of highly active antiretroviral therapy in a patient receiving maintenance fluconazole for a previous diagnosis of cryptococcal meningitis. We describe the unusual radiographic and histopathologic findings which are consistent with an immune reconstitution induced paradoxical inflammatory response to residual cryptococcal infection.
引用
收藏
页码:724 / 726
页数:3
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