Protein interactions and crystallization

被引：216

作者：

Rosenbaum, DF ^{[1
]}

Zukoski, CF ^{[1
]}

机构：

[1] UNIV ILLINOIS,DEPT CHEM ENGN,URBANA,IL 61801

来源：

JOURNAL OF CRYSTAL GROWTH | 1996年 / 169卷 / 04期

基金：

美国国家航空航天局;

关键词：

D O I：

10.1016/S0022-0248(96)00455-1

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

A lysozyme phase boundary is successfully compared to theoretical predictions from simple fluid theory. The comparison is made using the adhesive hard sphere potential to model protein interactions. The lysozyme phase boundary is constructed from solubility and osmotic second virial coefficient measurements. The result suggests simple models for protein interactions can be useful for investigating protein crystallization. This study supports the use of osmotic second virial coefficient measurements to identify favorable protein crystallization conditions.

引用

收藏

页码：752 / 758

页数：7

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