Effects of Central Kalimantan plant extracts on intraerythrocytic Babesia gibsoni in culture

被引:23
作者
Subeki
Matsuura, H
Yamasaki, M
Yamato, O
Maede, Y
Katakura, K
Suzuki, M
Trimurningish
Chairul
Yoshihara, T [1 ]
机构
[1] Hokkaido Univ, Grad Sch Agr, Div Appl Biosci, Bioorgan Chem Lab, Sapporo, Hokkaido 0608589, Japan
[2] Hokkaido Univ, Grad Sch Vet Med, Lab Internal Med, Dept Vet Clin Sci, Sapporo, Hokkaido 0600818, Japan
[3] Gunma Univ, Sch Med, Dept Parasitol, Maebashi, Gumma 3718511, Japan
[4] Indonesian Inst Sci, Dept Res & Dev Biol, Bogor 16122, Indonesia
关键词
D O I
10.1292/jvms.66.871
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The inhibitory effects of 45 plant extracts selected from Central Kalimantan, Indonesia on Babesia gibsoni in vitro and their acute toxicity to mice were evaluated. Of these plant extracts studied, Arcangelisia flava, Curcuma zedoaria, Garcinia benthamiana, Lansium domesticum and Peronema canescens were found to have appreciable antibabesial activity with IC50 values from 5.3 to 49.3,ug/ml without acute toxicity in mice at the intraperitoneal dose of 0.7 g/kg of body weight.
引用
收藏
页码:871 / 874
页数:4
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