Highly selective synthesis of menthols from citral in a one-step process

被引：76

作者：

Trasarti, AF ^{[1
]}

Marchi, AJ ^{[1
]}

Apesteguia, CR ^{[1
]}

机构：

[1] UNL, CONICET, Catalysis Sci & Engn Res Grp, Inst Invest Catalisis & Petroquim, RA-3000 Santa Fe, Argentina

来源：

JOURNAL OF CATALYSIS | 2004年 / 224卷 / 02期

关键词：

menthol synthesis; citral conversion; fine chemistry; sustainable processes;

D O I：

10.1016/j.jcat.2004.03.016

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We report for the first time the selective synthesis of menthols from citral in a one-step process. Bifunctional metal/acid catalysts active and selective for menthol synthesis were developed by studying the individual steps involved in the reaction pathway leading to menthols from citral. The metallic component was selected by testing silica-supported metals for citral hydrogenation to citronellal. Acid site requirements to efficiently isomerize citronellal to isopulegols were investigated on different solid acids. Potential bifunctional metal/acid catalysts were then prepared and tested for citral conversion to menthols. The best catalyst was Ni/Al-MCM-41, which yielded about 90% menthols and cave 70-75% of racemic (+/-)-menthol in the menthol mixture. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：484 / 488

页数：5

共 11 条

[1] Scandium trifluoromethanesulfonate, an efficient catalyst for the intermolecular carbonyl-ene reaction and the intramolecular cyclisation of citronellal. [J].