Quality control in self/nonself discrimination

被引：83

作者：

Boehm, Thomas ^{[1
]}

机构：

[1] Max Planck Inst Immunobiol, Dept Dev Immunol, Freiburg, Germany

来源：

CELL | 2006年 / 125卷 / 05期

关键词：

D O I：

10.1016/j.cell.2006.05.017

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Unicellular eukaryotes primarily employ self/nonself discrimination to avoid self-mating, whereas multicellular organisms also use self/nonself discrimination in immune defense. Recent advances in understanding self/nonself discrimination in eukaryotes shed new light on the emergence of the most sophisticated self/nonself discrimination system known, the antigen receptors employed in the adaptive immune system. © 2006 Elsevier Inc. All rights reserved.

引用

页码：845 / 858

页数：14

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