Towards the structure of the human immunodeficiency virus: divide and conquer?

被引:37
作者
Wilk, T [1 ]
Fuller, SD [1 ]
机构
[1] European Mol Biol Lab, Struct Biol Programme, D-69117 Heidelberg, Germany
关键词
D O I
10.1016/S0959-440X(99)80033-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent publications have expanded our knowledge of the major structural proteins of the human immunodeficiency virus as isolated proteins. The next challenge lies in understanding the changes in structure and the interactions of these components during assembly and maturation.
引用
收藏
页码:231 / 243
页数:13
相关论文
共 96 条
[1]   Spontaneous mutations in the human immunodeficiency virus type 1 gag gene that affect viral replication in the presence of cyclosporins [J].
Aberham, C ;
Weber, S ;
Phares, W .
JOURNAL OF VIROLOGY, 1996, 70 (06) :3536-3544
[2]  
BAKER TS, 1999, IN PRESS MICROBIOL M
[3]   Organization of HIV-1 capsid proteins on a lipid monolayer [J].
Barklis, E ;
McDermott, J ;
Wilkens, S ;
Fuller, S ;
Thompson, D .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (13) :7177-7180
[4]  
BARKLIS E, 1996, EMBO J, V16, P1199
[5]  
Berkowitz R, 1996, CURR TOP MICROBIOL, V214, P177
[6]   RETROVIRAL NUCLEOCAPSID DOMAINS MEDIATE THE SPECIFIC RECOGNITION OF GENOMIC VIRAL RNAS BY CHIMERIC GAG POLYPROTEINS DURING RNA PACKAGING IN-VIVO [J].
BERKOWITZ, RD ;
OHAGEN, A ;
HOGLUND, S ;
GOFF, SP .
JOURNAL OF VIROLOGY, 1995, 69 (10) :6445-6456
[7]  
BERTHETCOLOMINA.C, 1999, IN PRESS EMBO J
[8]   The C-terminal half of the human immunodeficiency virus type 1 Gag precursor is sufficient for efficient particle assembly [J].
Borsetti, A ;
Ohagen, Å ;
Göttlinger, HG .
JOURNAL OF VIROLOGY, 1998, 72 (11) :9313-9317
[9]   Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A [J].
Braaten, D ;
Aberham, C ;
Franke, EK ;
Yin, L ;
Phares, W ;
Luban, J .
JOURNAL OF VIROLOGY, 1996, 70 (08) :5170-5176
[10]   ULTRASTRUCTURAL EVIDENCE OF AN INTERACTION BETWEEN ENV AND GAG PROTEINS DURING ASSEMBLY OF HIV TYPE-1 [J].
BUGELSKI, PJ ;
MALEEFF, BE ;
KLINKNER, AM ;
VENTRE, J ;
HART, TK .
AIDS RESEARCH AND HUMAN RETROVIRUSES, 1995, 11 (01) :55-64