Enantioselective Aza-Darzens Reaction Catalyzed by A Chiral Phosphoric Acid

被引：120

作者：

Akiyama, Takahiko ^{[1
]}

Suzuki, Tohru ^{[1
]}

Mori, Keiji ^{[1
]}

机构：

[1] Gakushuin Univ, Dept Chem, Toshima Ku, Tokyo 1718588, Japan

来源：

ORGANIC LETTERS | 2009年 / 11卷 / 11期

关键词：

MANNICH-TYPE REACTION; DIELS-ALDER REACTION; BRONSTED ACID; ASYMMETRIC AZIRIDINATION; LEWIS-ACID; 1,3-DIPOLAR CYCLOADDITION; ADDITION-REACTIONS; IMINES; LIGANDS; VAPOL;

D O I：

10.1021/ol900674t

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

Aza-Darzens reaction of ethyl diazoacetate with aldimines, derived from phenyl glyoxal, furnished cis-aziridine carboxylates with excellent enantioselectivities by means of a chiral phosphoric acid.

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收藏

页码：2445 / 2447

页数：3

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