Idiopathic infantile arterial calcification: clinical presentation, therapy and long-term follow-up

被引：60

作者：

van der Sluis, Inge M.

Boot, Annemieke M.

Vernooij, Meike

Meradji, Morteza

Kroon, Andre A.

机构：

[1] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Dept Paediat, NL-3015 GJ Rotterdam, Netherlands

[2] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Div Endocrinol, NL-3015 GJ Rotterdam, Netherlands

[3] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Dept Paediat Radiol, NL-3015 GJ Rotterdam, Netherlands

[4] Sophia Childrens Univ Hosp, Erasmus Med Ctr, Div Neonatol, NL-3015 GJ Rotterdam, Netherlands

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 2006年 / 165卷 / 09期

关键词：

idiopathic infantile arterial calcification; bisphosphonates; therapy; diagnostics; long-term follow-up;

D O I：

10.1007/s00431-006-0146-8

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Idiopathic infantile arterial calcification (IIAC) is a rare disease characterised by extensive depositions of hydroxyapatite in the internal elastic lamina of medium-sized and large arteries, frequently accompanied by periarticular calcifications. We report on three patients with various presenting signs and symptoms. Diagnostic imaging techniques and therapy with bisphosphonates will be discussed. For the first time long-term follow-up of up to 25 years will be reported.

引用

页码：590 / 593

页数：4

共 15 条

[1] Fatal outcome of two siblings with idiopathic arterial calcification of infancy diagnosed in utero [J].