Hyphenated techniques

被引：12

作者：

Albert, K ^{[1
]}

Krucker, M ^{[1
]}

Glaser, T ^{[1
]}

Schefer, A ^{[1
]}

Lienau, A ^{[1
]}

Zeeb, D ^{[1
]}

机构：

[1] Univ Tubingen, Inst Organ Chem, D-72076 Tubingen, Germany

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2002年 / 372卷 / 01期

关键词：

D O I：

10.1007/s00216-001-1158-x

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The hyphenation of chromatographic separation techniques with spectroscopic identification is of increasing importance to fulfil the need for efficient and rapid on-line identification of peaks from a chromatographic separation. The combination of effective ion-line coupling of HPLC with ESI MS, APCI MS, and NMR has been shown to be extremely helpful for the solution of a myriad of separation and identification problems in pharmacy, biotechnology and nutrition. A sensitivity test of a 2.0-mm capillary HPLC-NMR probe with a detection volume of 750 nL is shown. This newly designed probe with a double-saddle Helmholtz coil results in significant improvements in signal line shape and easy magnetic-field homogenization.

引用

页码：25 / 26

页数：2

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