Growth and amino acid requirements of hyaluronic-acid-producing Streptococcus zooepidemicus

被引：60

作者：

Armstrong, DC ^{[1
]}

Cooney, MJ ^{[1
]}

Johns, MR ^{[1
]}

机构：

[1] UNIV QUEENSLAND,DEPT CHEM ENGN,BRISBANE,QLD 4072,AUSTRALIA

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 1997年 / 47卷 / 03期

基金：

澳大利亚研究理事会;

关键词：

CHEMICALLY DEFINED MEDIUM; STRAINS;

D O I：

10.1007/s002530050932

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A chemically defined medium has been developed for anaerobic cultivation of hyaluronic-acid(HA)-producing Streptococcus zooepidemicus, which contains 11 amino acids essential to growth, and glutamine as a principal nitrogen source. The final HA concentration, the specific rate of HA production and HA-to-glucose yields were similar for growth in the chemically defined medium relative to growth in complex medium. Consequently cells cultivated on chemically defined medium can be expected to have similar activity regarding HA synthesis as compared to cells grown on complex media. However, the specific growth rate and volumetric HA production rate were found to be less favourable in the chemically defined media.

引用

页码：309 / 312

页数：4

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