The reactivity of drimane unsaturated dialdehydes towards nucleophiles

被引：12

作者：

Jonassohn, M ^{[1
]}

Davidsson, R ^{[1
]}

Kahnberg, P ^{[1
]}

Sterner, O ^{[1
]}

机构：

[1] LUND UNIV, DEPT ORGAN CHEM 2, S-22100 LUND, SWEDEN

来源：

TETRAHEDRON | 1997年 / 53卷 / 01期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/S0040-4020(96)00966-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactivity of the potent antifeedants and antibiotics (-)-polygodial (1) and (-)-warburganal (3) [prepared from (-)-1] towards amino acids and triacetic acid lactone (5) was compared to that of their C-9 epimers 2 and 4 [both prepared from (-)-1]. Polygodial (1) reacts approximately 10 times faster than warburganal (3), which in turn is more reactive that the two epimers. The isolation and characterisation of adducts formed with 5 show that these drimanes react in a similar way as other bioactive sesquiterpenoid unsaturated dialdehydes. Copyright (C) 1996 Elsevier Science Ltd

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页码：237 / 244

页数：8

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