Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol

被引：29

作者：

Bailey, S

Davies, SG

Smith, AD

Withey, JM

机构：

[1] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England

[2] Pfizer Ltd, Global Res & Dev, IPC 818, Discovery Chem, Sandwich CT13 9NJ, Kent, England

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 23期

关键词：

D O I：

10.1039/b209728c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The asymmetric synthesis of (1R,2S,3R)-3-methyl-2-aminocyclopentane carboxylic acid has been achieved via kinetic resolution of racemic tert-butyl 3-methyl-cyclopentene-1-carboxylate with homochiral lithium (S)-N-benzyl-N-alpha-methylbenzylamide.

引用

页码：2910 / 2911

页数：2

共 17 条

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