Synthesis of benzonorcaradienes by gold(I)-catalyzed [4+3] annulation

被引：146

作者：

Gorin, David J. ^{[1
]}

Dube, Pascal ^{[1
]}

Toste, F. Dean ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 45期

关键词：

D O I：

10.1021/ja066694e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A formal [4 + 3]-annulation of vinyl arenes and diynyl propargyl esters is described. A mechanism involving cationic phosphinegold(I)-catalyzed tandem cyclopropanation/hydroarylation to produce the benzonorcaradiene products is proposed. In accord with this mechanism, the alkynyl cyclopropane can also be prepared with excellent regio- and diastereocontrol. Copyright © 2006 American Chemical Society.

引用

页码：14480 / 14481

页数：2

共 36 条

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