Fitness cost of SCCmec and methicillin resistance levels in staphylococcus aureus

被引:125
作者
Ender, M [1 ]
McCallum, N [1 ]
Adhikari, R [1 ]
Berger-Bächi, B [1 ]
机构
[1] Univ Zurich, Dept Med Microbiol, CH-8028 Zurich, Switzerland
关键词
D O I
10.1128/AAC.48.6.2295-2297.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Transformation of a type I SCCmec element into Staphylococcus aureus yielded highly oxacillin-resistant transformants with a reduced growth rate. Faster-growing variants could again be selected at the cost of reduced resistance levels, demonstrating an inverse correlation between oxacillin resistance levels and growth rate.
引用
收藏
页码:2295 / 2297
页数:3
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