Structures of flagranones A, B and C, cyclohexenoxide antibiotics from the nematode-trapping fungus Duddingtonia flagrans

被引:13
作者
Anderson, MG
Rickards, RW [1 ]
Lacey, E
机构
[1] Australian Natl Univ, Res Sch Chem, Canberra, ACT 0200, Australia
[2] Microbial Screening Technol Pty Ltd, Yarrandoo Res Stn, Kemps Creek, NSW 2171, Australia
关键词
D O I
10.7164/antibiotics.52.1023
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Spectroscopic data define the structures of the flagranones A (2), B (3) and C (4) from the nematode-trapping fungus Duddingtonia flagrans. These antibiotics are structurally related to the farnesylated cyclohexenoxides of the oligosporon group recently isolated from the nematode-trapping fungus Arthrobotrys oligospora, and show similar antimicrobial activity.
引用
收藏
页码:1023 / 1028
页数:6
相关论文
共 21 条
[1]   Phylogeny of nematode-trapping fungi based on 18S rDNA sequences [J].
Ahrén, D ;
Ursing, BM ;
Tunlid, A .
FEMS MICROBIOLOGY LETTERS, 1998, 158 (02) :179-184
[2]   STRUCTURES AND ABSOLUTE-CONFIGURATIONS OF ANTIBIOTICS OF THE OLIGOSPORON GROUP FROM THE NEMATODE-TRAPPING FUNGUS ARTHROBOTRYS OLIGOSPORA [J].
ANDERSON, MG ;
JARMAN, TB ;
RICKARDS, RW .
JOURNAL OF ANTIBIOTICS, 1995, 48 (05) :391-398
[3]  
[Anonymous], 1977, TOPICS MYCOBIOLOGY
[4]  
[Anonymous], DISEASES NEMATODES
[5]   The potential of nematophagous fungi to control the free-living stages of nematode parasites of sheep: Comparison between Australian isolates of Arthrobotrys spp. and Duddingtonia flagrans [J].
Faedo, M ;
Larsen, M ;
Waller, PJ .
VETERINARY PARASITOLOGY, 1997, 72 (02) :149-155
[6]   The preventive effect of the fungus Duddingtonia flagrans on trichostrongyle infections of lambs on pasture [J].
Githigia, SM ;
Thamsborg, SM ;
Larsen, M ;
Kyvsgaard, NC ;
Nansen, P .
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 1997, 27 (08) :931-939
[7]  
Lacey E., 1990, Resistance of parasites to antiparasitic drugs: Round Table Conference, ICOPA VII Paris 1990., P177
[8]   Phylogeny of the genus Arthrobotyrs and allied nematode-trapping fungi based on rDNA sequences [J].
Liou, GY ;
Tzean, SS .
MYCOLOGIA, 1997, 89 (06) :876-884
[9]   BIOSYNTHESIS OF EPOXYDON AND RELATED COMPOUNDS BY PHYLLOSTICTA SP [J].
NABETA, K ;
ICHIHARA, A ;
SAKAMURA, S .
AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1975, 39 (02) :409-413
[10]   PHYTOTOXINS FROM TEA GRAY BLIGHT FUNGI, PESTALOTIOPSIS-LONGISETA AND PESTALOTIOPSIS-THEAE [J].
NAGATA, T ;
ANDO, Y ;
HIROTA, A .
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1992, 56 (05) :810-811