STRUCTURES AND ABSOLUTE-CONFIGURATIONS OF ANTIBIOTICS OF THE OLIGOSPORON GROUP FROM THE NEMATODE-TRAPPING FUNGUS ARTHROBOTRYS OLIGOSPORA

被引：51

作者：

ANDERSON, MG ^{[1
]}

JARMAN, TB ^{[1
]}

RICKARDS, RW ^{[1
]}

机构：

[1] AUSTRALIAN NATL UNIV,RES SCH CHEM,CANBERRA,ACT 0200,AUSTRALIA

来源：

JOURNAL OF ANTIBIOTICS | 1995年 / 48卷 / 05期

关键词：

D O I：

10.7164/antibiotics.48.391

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Spectroscopic data define the structures of three new antibiotics, 4',5'-dihydro-oligosporon (4), hydroxyoligosporon (5) and 10',11'-epoxyoligosporon (6) from the nematode-trapping fungus Arthrobotrys oligospora, and confirm the structures of the recently reported antibiotics oligosporon (1) and oligosporol B (3). The absolute configuration of the substituted 7-oxabicyclo[4.1.0]hept-3-ene nucleus of these metabolites is determined by circular dichroic spectroscopy. Oligosporon (1) and its dihydro-derivative (4) represent the second and most complex structural type of nematocidal metabolite to be characterised from cultures of nematophagous fungi.

引用

页码：391 / 398

页数：8

共 23 条

[1]

ANDERSON MG, 1994, 14TH NAT C WOLL

[2]

Barron G.L., 1977, NEMATODE DESTROYING, VI, P144

[3]

BELLAMY LJ, 1975, INFRARED SPECTRA COM, P46

[4] DIE KONSTITUTION VON EPOXYDON [J].

CLOSSE, A ;

MAULI, R ;

SIGG, HP .

HELVETICA CHIMICA ACTA, 1966, 49 :204-+

[5] STEREOSPECIFIC TOTAL SYNTHESIS OF THE CYCLOHEXENE OXIDE ANTIBIOTIC EUPENOXIDE [J].

DUKE, RK ;

RICKARDS, RW .

JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (11) :1898-1904

[6] THE CHEMISTRY OF EREMOPHILA SPP .15. NEW ACYCLIC DITERPENES FROM EREMOPHILA SPP [J].

GHISALBERTI, EL ;

JEFFERIES, PR ;

PROUDFOOT, GM .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1981, 34 (07) :1491-1499

[7] UNPRECEDENTED CONSTITUENTS OF A NEW SPECIES OF ACORN WORM [J].

HIGA, T ;

OKUDA, RK ;

SEVERNS, RM ;

SCHEUER, PJ ;

HE, CH ;

XU, CF ;

CLARDY, J .

TETRAHEDRON, 1987, 43 (06) :1063-1070

[8]

Jansson H.-B., 1988, P59

[9] STRUCTURE OF PANEPOXYDONE AND RELATED FUNGI METABOLITES [J].

KIS, Z ;

CLOSSE, A ;

SIGG, HP ;

HRUBAN, L ;

SNATZKE, G .

HELVETICA CHIMICA ACTA, 1970, 53 (07) :1577-&

[10]

Lacey E., 1990, Resistance of parasites to antiparasitic drugs: Round Table Conference, ICOPA VII Paris 1990., P177

← 1 2 3 →