STRUCTURES AND ABSOLUTE-CONFIGURATIONS OF ANTIBIOTICS OF THE OLIGOSPORON GROUP FROM THE NEMATODE-TRAPPING FUNGUS ARTHROBOTRYS OLIGOSPORA

被引：51

作者：

ANDERSON, MG ^{[1
]}

JARMAN, TB ^{[1
]}

RICKARDS, RW ^{[1
]}

机构：

[1] AUSTRALIAN NATL UNIV,RES SCH CHEM,CANBERRA,ACT 0200,AUSTRALIA

来源：

JOURNAL OF ANTIBIOTICS | 1995年 / 48卷 / 05期

关键词：

D O I：

10.7164/antibiotics.48.391

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Spectroscopic data define the structures of three new antibiotics, 4',5'-dihydro-oligosporon (4), hydroxyoligosporon (5) and 10',11'-epoxyoligosporon (6) from the nematode-trapping fungus Arthrobotrys oligospora, and confirm the structures of the recently reported antibiotics oligosporon (1) and oligosporol B (3). The absolute configuration of the substituted 7-oxabicyclo[4.1.0]hept-3-ene nucleus of these metabolites is determined by circular dichroic spectroscopy. Oligosporon (1) and its dihydro-derivative (4) represent the second and most complex structural type of nematocidal metabolite to be characterised from cultures of nematophagous fungi.

引用

页码：391 / 398

页数：8

共 23 条

[11] BIOSYNTHESIS OF EPOXYDON AND RELATED COMPOUNDS BY PHYLLOSTICTA SP [J].

NABETA, K ;

ICHIHARA, A ;

SAKAMURA, S .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1975, 39 (02) :409-413

[12] ISOLATION AND STRUCTURE OF (+)-DESOXYEPIEPOXYDON AND (+)-EPIEPOXYDON, PHYTOTOXIC FUNGAL METABOLITES [J].

NAGASAWA, H ;

SUZUKI, A ;

TAMURA, S .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1978, 42 (06) :1303-1304

[13]

NORDBRINGHERTZ B, 1988, ADV MICROB ECOL, V10, P81

[14]

NORDBRINGHERTZ B, 1988, MICROBIOL SCI, V5, P108

[15] BIOSYNTHESIS OF PATULIN [J].

SCOTT, AI ;

ZAMIR, L ;

PHILLIPS, GT ;

YALPANI, M .

BIOORGANIC CHEMISTRY, 1973, 2 (02) :124-139

[16]

SCOTT AI, 1964, INTERPRETATION ULTRA, P52

[17] ISOEPOXYDON, A NEW METABOLITE OF THE PATULIN PATHWAY IN PENICILLIUM-URTICAE [J].

SEKIGUCHI, J ;

GAUCHER, GM .

BIOCHEMICAL JOURNAL, 1979, 182 (02) :445-453

[18]

STADLER M, 1993, ARCH MICROBIOL, V160, P401

[19]

STADLER M, 1993, Z NATURFORSCH C, V48, P843

[20]

STIRLING GR, 1988, DISEASES NEMATODES, V2, P93

← 1 2 3 →