Probabilistic atlas can improve reconstruction from optical imaging of the neonatal brain

被引:23
作者
Heiskala, Juha [1 ,2 ]
Pollari, Mika [2 ]
Metsaranta, Marjo [3 ]
Grant, P. Ellen [4 ,5 ]
Nissila, Ilkka [2 ]
机构
[1] Helsinki Univ Cent Hosp, HUSLAB, BioMag Lab, FI-00029 Helsinki, Finland
[2] Aalto Univ, Dept Biomed Engn & Computat Sci, FI-02015 Espoo, Finland
[3] Helsinki Univ Cent Hosp, Dept Pediat, FI-00029 Helsinki, Finland
[4] Childrens Hosp, Div Newborn Med, Boston, MA 02115 USA
[5] Childrens Hosp, Dept Radiol, Boston, MA 02115 USA
来源
OPTICS EXPRESS | 2009年 / 17卷 / 17期
基金
芬兰科学院;
关键词
SPATIAL REGISTRATION; INFANT BRAIN; MNI SPACE; HEAD; INFORMATION; TOMOGRAPHY; ACTIVATION; ADULT; SPECTROSCOPY; RESOLUTION;
D O I
10.1364/OE.17.014977
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Diffuse optical imaging is an emerging medical imaging modality based on near-infrared and visible red light. The method can be used for imaging activations in the human brain. In this study, a deformable probabilistic atlas of the distribution of tissue types within the term neonatal head was created based on MR images. The use of anatomical prior information provided by such atlas in reconstructing brain activations from optical imaging measurements was studied using Monte Carlo simulations. The results suggest that use of generic anatomical information can greatly improve the spatial accuracy and robustness of the reconstruction when noise is present in the data. (C) 2009 Optical Society of America
引用
收藏
页码:14977 / 14992
页数:16
相关论文
共 33 条
[1]   A FINITE-ELEMENT APPROACH FOR MODELING PHOTON TRANSPORT IN TISSUE [J].
ARRIDGE, SR ;
SCHWEIGER, M ;
HIRAOKA, M ;
DELPY, DT .
MEDICAL PHYSICS, 1993, 20 (02) :299-309
[2]   PHOTON-MEASUREMENT DENSITY-FUNCTIONS .1. ANALYTICAL FORMS [J].
ARRIDGE, SR .
APPLIED OPTICS, 1995, 34 (31) :7395-7409
[3]   Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy [J].
Boas, DA ;
Dale, AM ;
Franceschini, MA .
NEUROIMAGE, 2004, 23 :S275-S288
[4]  
Chandrasekhar S., 1960, RAD TRANSFER
[5]  
CUSTO A, 2008, THESIS MIT
[6]   Spatial extent of oxygen metabolism and hemodynamic changes during functional activation of the rat somatosensory cortex [J].
Dunn, AK ;
Devor, A ;
Dale, AM ;
Boas, DA .
NEUROIMAGE, 2005, 27 (02) :279-290
[7]   Whole brain segmentation: Automated labeling of neuroanatomical structures in the human brain [J].
Fischl, B ;
Salat, DH ;
Busa, E ;
Albert, M ;
Dieterich, M ;
Haselgrove, C ;
van der Kouwe, A ;
Killiany, R ;
Kennedy, D ;
Klaveness, S ;
Montillo, A ;
Makris, N ;
Rosen, B ;
Dale, AM .
NEURON, 2002, 33 (03) :341-355
[8]   Monte Carlo prediction of near-infrared light propagation in realistic adult and neonatal head models [J].
Fukui, Y ;
Ajichi, Y ;
Okada, E .
APPLIED OPTICS, 2003, 42 (16) :2881-2887
[9]   Three-dimensional whole-head optical passive motor evoked responses in the tomography of neonate [J].
Gibson, AP ;
Austin, T ;
Everdell, NL ;
Schweiger, M ;
Arridge, SR ;
Meek, JH ;
Wyatt, JS ;
Delpy, DT ;
Hebden, JC .
NEUROIMAGE, 2006, 30 (02) :521-528
[10]   Diffuse optical tomography with a priori anatomical information [J].
Guven, M ;
Yazici, B ;
Intes, X ;
Chance, B .
PHYSICS IN MEDICINE AND BIOLOGY, 2005, 50 (12) :2837-2858