Outcome of subsequent pregnancy in patients with documented peripartum cardiomyopathy

被引:55
作者
Sliwa, K [1 ]
Forster, O [1 ]
Zhanje, F [1 ]
Candy, G [1 ]
Kachope, J [1 ]
Essop, R [1 ]
机构
[1] Univ Witwatersrand, Chris Hani Baragwanath Hosp, Dept Cardiol, Johannesburg, South Africa
关键词
D O I
10.1016/j.amjcard.2004.02.053
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Subsequent pregnancy in 6 patients with, previous peripartum cardiomyopathy resulted in reduction of ejection fraction by >10% in 5 patients at 1 month postportum. Two patients with impaired ejection fraction at onset of subsequent pregnancy died 3 months postpartum-due to heart failure despite optimal medical therapy. Deterioration of left ventricular function occurred uniformly postpartum and was accompanied by elevation of tumor necrosis factor-a plasma levels from 2.4 +/- 1.1 pg/ml at onset of subsequent pregnancy to 6.2 +/- 2.4 pg/ml at 1 month postpartum. (C)2004 by Excerpta Medica, Inc.
引用
收藏
页码:1441 / 1443
页数:3
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