学术探索
学术期刊
新闻热点
数据分析
智能评审

Mitochondrial control of apoptosis

被引：1382
作者：
Kroemer, G
Zamzami, N
Susin, SA
机构：
[1] CNRS UPR 420, F-94801 Villejuif, 19 rue Guy Moquet
来源：
IMMUNOLOGY TODAY | 1997年 / 18卷 / 01期
关键词：
D O I：
10.1016/S0167-5699(97)80014-X
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The apoptotic process can be subdivided into three phases: a death-stimulus-dependent, heterogeneous induction phase, a common effector phase during which the 'decision to die' is taken, and a common degradation phase during which cells acquire the biochemical and morphological features of end-stage apoptosis. Here, Guido Kroemer, Naoufal Zamzami and Santos Susin discuss the implication of mitochondrial events in the apoptotic effector phase.
引用
收藏
页码：44 / 51
页数：8
相关论文
共 71 条
  • [21] Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
    Graeber, TG
    Osmanian, C
    Jacks, T
    Housman, DE
    Koch, CJ
    Lowe, SW
    Giaccia, AJ
    [J]. NATURE, 1996, 379 (6560) : 88 - 91
  • [22] Role of mitochondria and C-terminal membrane anchor of Bcl-2 in Bax induced growth arrest and mortality in Saccharomyces cerevisiae
    Greenhalf, W
    Stephan, C
    Chaudhuri, B
    [J]. FEBS LETTERS, 1996, 380 (1-2) : 169 - 175
  • [23] PROTECTION BY CYCLOSPORINE-A OF ISCHEMIA REPERFUSION-INDUCED DAMAGE IN ISOLATED RAT HEARTS
    GRIFFITHS, EJ
    HALESTRAP, AP
    [J]. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1993, 25 (12) : 1461 - 1469
  • [24] STRUCTURE-FUNCTION ANALYSIS OF BCL-2 PROTEIN IDENTIFICATION OF CONSERVED DOMAINS IMPORTANT FOR HOMODIMERIZATION WITH BCL-2 AND HETERODIMERIZATION WITH BAX
    HANADA, M
    AIMESEMPE, C
    SATO, T
    REED, JC
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (20) : 11962 - 11969
  • [25] C-ELEGANS CELL-SURVIVAL GENE CED-9 ENCODES A FUNCTIONAL HOMOLOG OF THE MAMMALIAN PROTOONCOGENE BCL-2
    HENGARTNER, MO
    HORVITZ, HR
    [J]. CELL, 1994, 76 (04) : 665 - 676
  • [26] HENNET T, 1993, CANCER RES, V53, P1456
  • [27] HICKISH T, 1994, CANCER RES, V54, P2808
  • [28] BCL-2 FUNCTIONS IN AN ANTIOXIDANT PATHWAY TO PREVENT APOPTOSIS
    HOCKENBERY, DM
    OLTVAI, ZN
    YIN, XM
    MILLIMAN, CL
    KORSMEYER, SJ
    [J]. CELL, 1993, 75 (02) : 241 - 251
  • [29] Hunter JJ, 1996, MOL CELL BIOL, V16, P877
  • [30] IMBERTI R, 1993, J PHARMACOL EXP THER, V265, P392
12345678