Soft Listeria:: Actin-based propulsion of liquid drops -: art. no. 061906

被引：87

作者：

Boukellal, H

Campás, O

Joanny, JF

Prost, J

Sykes, C

机构：

[1] Inst Curie, UMR 168, F-75248 Paris 05, France

[2] Univ Barcelona, Dept ECM, E-08028 Barcelona, Spain

[3] Ecole Super Phys & Chim Ind Ville Paris, F-75231 Paris 05, France

来源：

PHYSICAL REVIEW E | 2004年 / 69卷 / 06期

关键词：

D O I：

10.1103/PhysRevE.69.061906

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

We study the motion of oil drops propelled by actin polymerization in cell extracts. Drops deform and acquire a pearlike shape under the action of the elastic stresses exerted by the actin comet, a tail of cross-linked actin filaments. We solve this free boundary problem and calculate the drop shape taking into account the elasticity of the actin gel and the variation of the polymerization velocity with normal stress. The pressure balance on the liquid drop imposes a zero propulsive force if gradients in surface tension or internal pressure are not taken into account. Quantitative parameters of actin polymerization are obtained by fitting theory to experiment.

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