Synthesis of thiol-linked neoglycopolymers and thermo-responsive glycomicelles as potential drug carrier

被引:164
作者
Chen, Gaojian [1 ]
Amajjahe, Sadik [1 ]
Stenzel, Martina H. [1 ]
机构
[1] Univ New S Wales, CAMD, Sch Chem Sci & Engn, Sydney, NSW 2052, Australia
关键词
MULTIVALENT LIGANDS; CLICK CHEMISTRY; SWEET SPOT; POLYMERIZATION; GLYCOPOLYMERS; POLYMERS; BINDING; GLYCOBIOLOGY; BIOLOGY; DESIGN;
D O I
10.1039/b900215d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Homopolymer and block copolymer bearing carbohydrate side chain functionality were obtained by grafting glucothiose onto alkene functional scaffolds via a thiol-ene click reaction and the resulting copolymer was used to form thermo-responsive micelles as a potential drug carrier.
引用
收藏
页码:1198 / 1200
页数:3
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