Rotaviruses are a major cause of hospitalizations for acute gastroenteritis in developed countries. This review shows the burden of rotavirus disease in < 5-year-old children in Europe. An estimated 72 000-77 000 hospitalizations for community-acquired rotavirus disease occur annually in the 23 million under-fives living in the European Union (EU-25), with a median cost of E1417 per case. Annual hospitalization incidence rates range from 0(.)3 to 11(.)9/1000 children < 5 years old (median 3/1000). The median proportion of hospital-acquired rotavirus disease among all cases of hospitalization for rotavirus disease is estimated to be 21%. Countries of the EU-25 require information on the burden of rotavirus disease to support introduction of rotavirus vaccines. Data on cases treated at home, medical visits, and emergency wards as well as rotavirus-associated deaths are limited. To fully evaluate the impact and effectiveness of rotavirus vaccination programmes in Europe, additional epidemiological studies will be critical and desirable.
机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Thuret, A
Patural, H
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Patural, H
Berthelot, P
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Berthelot, P
Benzait, F
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Benzait, F
Martin, I
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Martin, I
Jusot, JF
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Jusot, JF
Teyssier, G
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Teyssier, G
Fabry, J
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Fabry, J
Pozzetto, B
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CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, FranceCHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Thuret, A
Patural, H
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Patural, H
Berthelot, P
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Berthelot, P
Benzait, F
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Benzait, F
Martin, I
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Martin, I
Jusot, JF
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Jusot, JF
Teyssier, G
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机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Teyssier, G
Fabry, J
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h-index: 0
机构:CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France
Fabry, J
Pozzetto, B
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CHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, FranceCHU St Etienne, Hop Nord, Lab Bacteriol Virol Hyg, F-42055 St Etienne 02, France