Epidemiology of Group B streptococcus isolated from pregnant women in Beijing, China

被引:94
作者
Lu, B. [1 ]
Li, D. [2 ]
Cui, Y. [2 ]
Sui, W. [1 ]
Huang, L. [3 ]
Lu, X. [1 ]
机构
[1] Capital Med Univ, Beijing Tongren Hosp, Dept Lab Med, Beijing 100730, Peoples R China
[2] Civil Aviat Gen Hosp, Dept Lab Med, Beijing, Peoples R China
[3] Peking Univ, Dept Lab Med, Hosp 1, Beijing 100871, Peoples R China
关键词
Antibiotic resistance; colonization rate; Group B streptococcus; multilocus sequence typing; serotyping; MULTIPLEX PCR ASSAY; ERYTHROMYCIN; RESISTANCE; CLINDAMYCIN; PREVALENCE; PENICILLIN; AGALACTIAE; SEROTYPES;
D O I
10.1111/1469-0691.12416
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Group B Streptococcus (GBS) was the main causative organism of invasive infections in newborns due to vertical transmission from the colonized mothers. The study was undertaken to determine colonization rate, serotype distribution, genotypic characterization, antibiotic susceptibility profiles and molecular characteristics of erythromycin-resistant strains of GBS in pregnant women in Beijing, China. Vaginal-rectal swabs were collected from a total of 2850 pregnant women at 35-37 weeks of gestation, in which 7.1% were GBS positive. Serotypes III, Ia and V predominated. All isolates were penicillin susceptible, whereas the resistance rates for erythromycin and clindamycin were strikingly high.
引用
收藏
页码:O370 / O373
页数:4
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