Investigating cis-acting regulatory variation using assays of relative allelic expression

被引:14
作者
Bray, Nicholas J. [1 ]
O'Donovan, Michael C. [1 ]
机构
[1] Cardiff Univ, Sch Med, Dept Psychol Med, Cardiff CF14 4XN, Wales
关键词
allelic; haplotypes; epigenetic; gene expression; method;
D O I
10.1097/01.ypg.0000218612.35139.84
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Assays of relative allelic expression offer a powerful means of exploring the influence of cis-acting regulatory variation. In this article, we provide a general assay protocol and discuss practical and theoretical considerations for the design and interpretation of relative allelic expression analysis.
引用
收藏
页码:173 / 177
页数:5
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