A decline in mupirocin resistance in methicillin-resistant Staphylococcus aureus accompanied administrative control of prescriptions

被引：34

作者：

Walker, ES ^{[1
]}

Levy, F

Shorman, M

David, G

Abdalla, J

Sarubbi, FA

机构：

[1] James H Quillen VAMC, Mountain Home, TN 37684 USA

[2] E Tennessee State Univ, James H Quillen Coll Med, Dept Internal Med, Johnson City, TN 37614 USA

[3] E Tennessee State Univ, James H Quillen Coll Med, Dept Biol Sci, Johnson City, TN 37614 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2004年 / 42卷 / 06期

关键词：

D O I：

10.1128/JCM.42.6.2792-2795.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Susceptibility to mupirocin was assessed in methicillin-resistant Staphylococcus aureus isolates selected from eras corresponding to differences in usage rate and prescription policies at a Veterans Affairs medical center. The eras studied encompassed from the time of introduction of the drug to its widespread use, through recommended judicious use, and finally to subsequent stringent administrative control. Prescriptions declined from 3.0 to 0.1 per 1,000 patient days. Precipitous declines first in the numbers of isolates with high-level resistance (from 31% to 4%) and then in those with low-level resistance (from 26% to 10%) accompanied prescription control.

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页码：2792 / 2795

页数：4

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