Anti-Pseudomonas aeruginosa xanthones from the resin and green fruits of Cratoxylum cochinchinense

被引：49

作者：

Boonnak, Nawong ^{[1
,2
,3
]}

Karalai, Chatchanok ^{[1
,2
,3
]}

Chantrapromma, Suchada ^{[1
]}

Ponglimanont, Chanita ^{[2
,3
]}

Fun, Hoong-Kun ^{[4
]}

Kanjana-Opas, Akkharawit ^{[5
]}

Chantrapromma, Kan ^{[6
]}

Kato, Shigeru ^{[7
]}

机构：

[1] Prince Songkla Univ, Fac Sci, Dept Chem, Crystal Mat Res Unit, Hat Yai 90112, Songkhla, Thailand

[2] Prince Songkla Univ, Dept Chem, Hat Yai 90112, Songkhla, Thailand

[3] Prince Songkla Univ, Fac Sci, Ctr Excellence Innovat Chem, Hat Yai 90112, Songkhla, Thailand

[4] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, George Town 11800, Malaysia

[5] Prince Songkla Univ, Fac Agro Ind, Dept Ind Biotechnol, Hat Yai 90112, Songkhla, Thailand

[6] Walailak Univ, Inst Res & Dev, Thasala 80160, Nakhon St Thamm, Thailand

[7] Seikei Univ, Dept Mat & Life Sci, Tokyo 1808633, Japan

来源：

TETRAHEDRON | 2009年 / 65卷 / 15期

关键词：

Cratoxylum cochinchinense; 1,3,7-Trihydroxyxanthone; 1,3,7-Trioxygenated xanthone; Antifungal activity; Antibacterial activity; Pseudomonas aeruginosa; PRENYLATED XANTHONES; DERIVATIVES; BACTERIAL;

D O I：

10.1016/j.tet.2009.01.083

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

Cochinchinones 1-L (1-3 and 13) along with 11 known xanthones (4-12,14, and 15) were isolated from the resin and green fruits of Cratoxylum cochinchinense. In addition, four new acetylated compounds (1619) were derivatized from 7-geranyloxy-1,3-dihydroxyxanthone (14) and 3-geranyloxy-1,7-dihydroxyxanthone (15). All compounds were characterized on the basis of spectroscopic analyses. The structures of cochinchinone I (1), a monoacetate (18) and a dibrosylate (20), were also confirmed by X-ray diffraction analysis. The antibacterial and antifungal activities of selected Compounds were evaluated as well. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：3003 / 3013

页数：11

共 27 条

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